PGK1 polyclonal (Center), anti-human

PGK1 polyclonal (Center), anti-human

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In stock
SKU
AC-AP7094b
Catalog Number: AC-AP7094b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB05463
Applications: IHC-P, WB, FC, IF
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Background:
Also known as ATP:3-phosphoglycerate 1-phosphotransferase (EC 2.7.2.3), this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. New blood vessel formation or angiogenesis is critical for tumor expansion and metastasis. Lay et al. (2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. They concluded that phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and participates in the angiogenic process as a disulfide reductase.

Other Names:
Phosphoglycerate kinase 1, Cell migration-inducing gene 10 protein, Primer recognition protein 2, PRP 2, PGK1, PGKA

Target/Specificity:
This PGK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the Central region of human PGK1.

Antigen Region:
117-145

Antigen Type: Synthetic Peptide

Gene Name: PGK1
Gene ID: 5230
Primary Accession: P00558
NCBI Accession: NP_000282.1
Other Accession: P16617; P09411; Q60HD8; P00559
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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