PGR (clone 8A11H1), anti-human

Protein Family: Receptors and Channels, Transcription Factors

Pathway and Disease: Cancers, Cell Growth and Death, Signaling Molecules and Interaction, Transcription

Description:
PR (Progesterone receptor) is a transcription factor that is regulated by the binding of their cognate ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A functions as a transcriptional inhibitor of all steroid hormone receptors.

Alternate Names: Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3

Application Notes: WB: 1:500-1:2000

Accession No.: P06401

Antigen: Purified recombinant fragment of PGR(aa730-871) expressed in E. coli.

Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.