PGR/PR monoclonal (Ascites), anti-human
€470.00
In stock
SKU
AC-AM1958a
Catalog Number: AC-AM1958a
Size: 100 µl
Isotype: mouse IgM
Clone Name: 312CT8.2.1.6
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgM
Clone Name: 312CT8.2.1.6
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.
Other Names:
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3
Target/Specificity:
This PGR/PR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from human PGR/PR.
Antigen Region:
349-377
Antigen Type: Synthetic Peptide
Gene Name: PGR
Gene ID: 5241
Primary Accession: P06401
NCBI Accession: NP_000917.3;NP_001189403.1;NP_001258091.1
Other Accession: NP_000917.3
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.
Other Names:
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3
Target/Specificity:
This PGR/PR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from human PGR/PR.
Antigen Region:
349-377
Antigen Type: Synthetic Peptide
Gene Name: PGR
Gene ID: 5241
Primary Accession: P06401
NCBI Accession: NP_000917.3;NP_001189403.1;NP_001258091.1
Other Accession: NP_000917.3
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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