PGR/PR polyclonal (C-term), anti-human

PGR/PR polyclonal (C-term), anti-human

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In stock
SKU
AC-AP19260b
Catalog Number: AC-AP19260b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41081
Applications: WB, IF
Datasheet

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Background:
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

Other Names:
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3

Target/Specificity:
This PGR/PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-843 amino acids from the C-terminal region of human PGR/PR.

Antigen Region:
816-843

Antigen Type: Synthetic Peptide

Gene Name: PGR
Gene ID: 5241
Primary Accession: P06401
NCBI Accession: NP_000917.3;NP_001189403.1;NP_001258091.1
Other Accession: NP_000917.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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