PHB antibody (clone 3F4-2B2), anti-human
€435.00
In stock
SKU
AC-AT3292a
Catalog Number: AC-AT3292a
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IHC, IF, E
Request Information AC-AT3292a">Request Information
Background:
Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Other Names:
Prohibitin, PHB
Antigen Type:
Recombinant Protein
Gene Name: PHB1 {ECO:0000303|PubMed:28017329, ECO:0000312|HGNC:HGNC:8912}
Gene ID: 5245
NCBI Accession: NP_001268425.1;NP_001268644.1;NP_002625.1
Primary Accession: P35232
Other Accession: BC013401
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Other Names:
Prohibitin, PHB
Antigen Type:
Recombinant Protein
Gene Name: PHB1 {ECO:0000303|PubMed:28017329, ECO:0000312|HGNC:HGNC:8912}
Gene ID: 5245
NCBI Accession: NP_001268425.1;NP_001268644.1;NP_002625.1
Primary Accession: P35232
Other Accession: BC013401
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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