PHB polyclonal, anti-human, mouse, rat

Background:
Prohibitin is an evolutionarily conserved protein that has antiproliferative activity. The gene encoding human prohibitin maps to chromosome 17q21 and is ubiquitously expressed. Prohibitin is a post-synthetically modified protein that is localized in the inner membrane of mitochondria, where it regulates the cell cycle by blocking the transition between the G1 and S phases, and on the plasma membrane of B cells, where it mediates B cell maturation.

Alternative Name:
Prohibitin

Application Dilution: WB: 1:500 - 1:2000

Specificity: PHB polyclonal antibody detects endogenous levels of PHB protein.

Immunogen:
Recombinant full length Human PHB.

MW: ~ 30 kDa

Swis Prot.: P35232

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.