PHD2 / prolyl hydroxylase monoclonal, anti-human

PHD2 / prolyl hydroxylase monoclonal, anti-human

€455.00
In stock
SKU
AC-ABO14443
Catalog Number: AC-ABO14443
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IP
Datasheet
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Description: Anti-PHD2 / prolyl hydroxylase Monoclonal Antibody . Tested in WB, IP applications. This antibody reacts with Human.

Other Names: Egl nine homolog 1, 1.14.11.29, Hypoxia-inducible factor prolyl hydroxylase 2, HIF-PH2, HIF-prolyl hydroxylase 2, HPH-2, Prolyl hydroxylase domain-containing protein 2, PHD2, SM-20, EGLN1 (HGNC:1232), C1orf12

Clone Name(s):
Clone: ACEF-5

Gene ID: 54583

Immunogen: A synthesized peptide derived from human PHD2 / prolyl hydroxylase Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Calculated MW: 46021

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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