PHF6 Polyclonal Antibody

Background:
This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by cognitive disability, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
AC004383.6, BFLS, BORJ, CENP 31, Centromere protein 31, MGC14797, OTTHUMP00000024063, PHD finger protein 6, PHD like zinc finger protein, PHD-like zinc finger protein, Phf6, PHF6

Immunogen: Fusion protein of human PHF6

Swissprot: Q8IWS0
Gene Accession: BC005994

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.5 mg/mL
Dilution: IHC 1:100-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.