PHGDH polyclonal, anti-human, mouse, rat

Background:
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.

Synonyms: PDG, PGD, PGAD, PGDH, SERA, 3PGDH, 3-PGDH, HEL-S-113

Immunogen:
A synthetic peptide of human PHGDH

Gene Symbol: PHGDH

Gene ID: 26227

Swiss prot: O43175

Calculated MW: 57kDa

Recommended dilution:
WB 1:200-1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.