PHKA1/2 Polyclonal Antibody

Background:
phosphorylase kinase regulatory subunit alpha 1(PHKA1) Homo sapiens Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript varian

Alternative Names:
PHKA1, PHKA, Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform, Phosphorylase kinase alpha M subunit, PHKA2, PHKLA, PYK, Phosphorylase b kinase regulatory subunit alpha, liver

Immunogen: The antiserum was produced against synthesized peptide derived from human KPB1/2. AA range:31-80

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 137

GeneID: PHKA1/PHKA2

Storage: -20°C/1 year

NOTE: For Research Use Only