PHLPP1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

Synonyms: PHLPP, PLEKHE1, PPM3A, SCOP

Cellular Location: Cell membrane Cytoplasm Membrane Nucleus Peripheral membrane protein

Immunogen:
Recombinant protein of human PHLPP1

Gene Symbol: PHLPP1

Gene ID: 23239

Swiss prot: O60346

Calculated MW: 185kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.