PHLPP1 Polyclonal Antibody

Background:
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

Research Area: Cancer, Signal Transduction

Synonyms:
PHLPP1, PHLPP, PLEKHE1, PPM3A, SCOP

Immunogen: Recombinant fusion protein of human PHLPP1 (NP_919431.2).

Swissprot: O60346
Gene ID: 23239

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.