Phospho-ATF-2 polyclonal, anti-human, mouse, rat antibody
€355.00
In stock
SKU
AC-ABV10262-100
Catalog Number: AC-ABV10262-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
Request Information
Background:
The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 forms homodimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr69 and Thr71 by stress-activated kinases is necessary for transcriptional activation. Myc also induces phosphorylation of ATF-2 at Thr69 and Thr71 to prolong the half-life of ATF-2. ATF-2 also functions as a histone acetyltransferase (HAT) by specifically acetylating histones H2B and H4 in vitro.
Other Names:
ATF2, HB16, CREB2, CREBP1, CRE-BP1, CRE-BP1, TREB7, MGC111558, Cyclic AMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, cAMP response element-binding protein CRE-BP1, HB16, Cyclic AMP-responsive element-binding protein 2, cAMP-responsive element-binding protein 2, CREB-2.
Primary Accession: P15336
Gene Name: ATF2
Gene ID: 1386
Concentration (mg/ml): 0.5 mg/ml
The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 forms homodimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr69 and Thr71 by stress-activated kinases is necessary for transcriptional activation. Myc also induces phosphorylation of ATF-2 at Thr69 and Thr71 to prolong the half-life of ATF-2. ATF-2 also functions as a histone acetyltransferase (HAT) by specifically acetylating histones H2B and H4 in vitro.
Other Names:
ATF2, HB16, CREB2, CREBP1, CRE-BP1, CRE-BP1, TREB7, MGC111558, Cyclic AMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, cAMP response element-binding protein CRE-BP1, HB16, Cyclic AMP-responsive element-binding protein 2, cAMP-responsive element-binding protein 2, CREB-2.
Primary Accession: P15336
Gene Name: ATF2
Gene ID: 1386
Concentration (mg/ml): 0.5 mg/ml
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