Phospho-ATF4 (Ser219) rabbit polyclonal, anti-human

Backgroud: ATF4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway. ER stress represses the translation of the majority of mRNAs, but selectively stimulates the translation of certain mRNAs including that of ATF-4. Induced expression of ATF-4 increases the expression of genes critical for the recovery from ER stress.

Synonyms: Cyclic AMP-dependent transcription factor ATF-4, CREB-2, cAMP-responsive element-binding protein 2, DNA-binding protein TAXREB67

Gene Name: ATF4

Gene ID: 468

SwissProt ID: P18848

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.