Phospho-BACE(S498) polyclonal, anti-human
€0.00
In stock
SKU
AC-AP3032a
Catalog Number: AC-AP3032a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7137
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7137
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Other Names:
Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149
Target/Specificity:
This BACE Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S498 of human BACE.
Antigen Type: Synthetic Peptide
Gene Name: BACE1 (HGNC:933)
Gene ID: 23621
Primary Accession: P56817
NCBI Accession: NP_001193978.1;NP_036236.1;NP_620427.1;NP_620428.1;NP_620429.1
Other Accession: P56819; P56818; Q2HJ40
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Other Names:
Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149
Target/Specificity:
This BACE Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S498 of human BACE.
Antigen Type: Synthetic Peptide
Gene Name: BACE1 (HGNC:933)
Gene ID: 23621
Primary Accession: P56817
NCBI Accession: NP_001193978.1;NP_036236.1;NP_620427.1;NP_620428.1;NP_620429.1
Other Accession: P56819; P56818; Q2HJ40
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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