Phospho-Caspase 6(S257) polyclonal, anti-human
€0.00
In stock
SKU
AC-AP3043a
Catalog Number: AC-AP3043a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB06896
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB06896
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Caspase 6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.
Other Names:
Caspase-6, CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11, CASP6, MCH2
Target/Specificity:
This Caspase 6 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S257 of human Caspase 6.
Antigen Type: Synthetic Peptide
Gene Name: CASP6 (HGNC:1507)
Gene ID: 839
Primary Accession: P55212
NCBI Accession: NP_001217.2;NP_116787.1
Other Accession: O35397; O08738; Q3T0P5
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Caspase 6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.
Other Names:
Caspase-6, CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11, CASP6, MCH2
Target/Specificity:
This Caspase 6 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S257 of human Caspase 6.
Antigen Type: Synthetic Peptide
Gene Name: CASP6 (HGNC:1507)
Gene ID: 839
Primary Accession: P55212
NCBI Accession: NP_001217.2;NP_116787.1
Other Accession: O35397; O08738; Q3T0P5
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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