Phospho-CCND3(T283) polyclonal, anti-human
€0.00
In stock
SKU
AC-AP3870a
Catalog Number: AC-AP3870a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42083
Applications: DB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42083
Applications: DB
Datasheet
Request Information
Background:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
Other Names:
G1/S-specific cyclin-D3, CCND3
Target/Specificity:
This CCND3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T283 of human CCND3.
Antigen Type: Synthetic Peptide
Gene Name: CCND3 {ECO:0000303|PubMed:1386336, ECO:0000312|HGNC:HGNC:1585}
Gene ID: 896
Primary Accession: P30281
NCBI Accession: NP_001129489.1;NP_001129597.1;NP_001129598.1;NP_001751.1
Other Accession: P48961; P30282; Q3MHH5; NP_001129489.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
Other Names:
G1/S-specific cyclin-D3, CCND3
Target/Specificity:
This CCND3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T283 of human CCND3.
Antigen Type: Synthetic Peptide
Gene Name: CCND3 {ECO:0000303|PubMed:1386336, ECO:0000312|HGNC:HGNC:1585}
Gene ID: 896
Primary Accession: P30281
NCBI Accession: NP_001129489.1;NP_001129597.1;NP_001129598.1;NP_001751.1
Other Accession: P48961; P30282; Q3MHH5; NP_001129489.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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