Phospho-CDK2(T160) Polyclonal Antibody

Background:
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
CDK2, CDKN2, p33(CDK2)

Immunogen: A phospho specific peptide corresponding to residues surrounding T160 of human CDK2

Swissprot: P24941
Gene ID: 1017

Calculated MW: 30 kDa/33 kDa
Observed MW: 34 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.