Phospho-CDX2(S283) polyclonal, anti-human
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In stock
SKU
AC-AP3701a
Catalog Number: AC-AP3701a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16600
Applications: WB, DB, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16600
Applications: WB, DB, IF
Datasheet
Request Information
Background:
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.
Other Names:
Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2, CDX2, CDX3
Target/Specificity:
This CDX2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S283 of human CDX2.
Antigen Type: Synthetic Peptide
Gene Name: CDX2
Gene ID: 1045
Primary Accession: Q99626
NCBI Accession: NP_001256.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.
Other Names:
Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2, CDX2, CDX3
Target/Specificity:
This CDX2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S283 of human CDX2.
Antigen Type: Synthetic Peptide
Gene Name: CDX2
Gene ID: 1045
Primary Accession: Q99626
NCBI Accession: NP_001256.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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