Phospho-CREB1(S133) Polyclonal Antibody

Background:
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology

Synonyms:
CREB1, CREB, CREB-1

Immunogen: A phospho specific peptide corresponding to residues surrounding S133 of human CREB1

Swissprot: P16220
Gene ID: 1385

Calculated MW: 25 kDa/35 kDa/36 kDa
Observed MW: 43 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:1000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.