Phospho-EEF2K (Ser366) Polyclonal Antibody

Background:
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
C86191, Calcium/calmodulin dependent eukaryotic elongation factor 2, Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, Calmodulin dependent protein kinase III, cb365, EC 2.7.11.20, eEF 2 kinase, eEF 2K, eEF-2 kinase, eEF-2K, Eef2k, EEF2K protein, EF2K, Elongation factor 2 kinase, Eukaryotic elongation factor 2 kinase, fa04b08, HSU93850, kinase eEF2K, MGC45041, SMEF2K, wu:fa04b08, zgc:100973

Immunogen: Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366

Swissprot: O00418

Calculated MW: 82 kDa
Observed MW: 105 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-21641/sc-21642