Phospho-EGFR(Y998) polyclonal, anti-human

Phospho-EGFR(Y998) polyclonal, anti-human

€0.00
In stock
SKU
AC-AP3384a
Catalog Number: AC-AP3384a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB11058
Applications: WB, DB
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Background:
Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. EGFR is a receptor for EGF, but also for other members of the EGF family, including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation.

Other Names:
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1

Target/Specificity:
This EGFR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y998 of human EGFR.

Antigen Type: Synthetic Peptide

Gene Name: EGFR (HGNC:3236)
Gene ID: 1956
Primary Accession: P00533
NCBI Accession: NP_005219.2;NP_958439.1;NP_958440.1;NP_958441.1
Other Accession: Q01279
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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