Phospho-eIF2α(S51) Polyclonal Antibody

Background:
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A, EIF2S1

Immunogen: A synthetic phosphorylated peptide around S51 of human eIF2α (NP_004085.1).

Swissprot: P05198
Gene ID: 1965

Calculated MW: 36 kDa
Observed MW: 38 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.