Phospho-eNOS(S1177) Polyclonal Antibody

Background:
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants.

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience

Synonyms:
NOS3, ECNOS, eNOS

Immunogen: A synthetic phosphorylated peptide around S1177 of human eNOS (NP_000594.2).

Swissprot: P29474
Gene ID: 4846

Calculated MW: 67 kDa/68 kDa/133 kDa
Observed MW: 133 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.