Phospho-EP300(S1834) polyclonal, anti-human
€0.00
In stock
SKU
AC-AP3842a
Catalog Number: AC-AP3842a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41431
Applications: DB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41431
Applications: DB
Datasheet
Request Information
Background:
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
Other Names:
Histone acetyltransferase p300, p300 HAT, E1A-associated protein p300, EP300, P300
Target/Specificity:
This EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human EP300.
Antigen Type: Synthetic Peptide
Gene Name: EP300 {ECO:0000303|PubMed:15706485, ECO:0000312|HGNC:HGNC:3373}
Gene ID: 2033
Primary Accession: Q09472
NCBI Accession: NP_001420.2
Other Accession: NP_001420.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
Other Names:
Histone acetyltransferase p300, p300 HAT, E1A-associated protein p300, EP300, P300
Target/Specificity:
This EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human EP300.
Antigen Type: Synthetic Peptide
Gene Name: EP300 {ECO:0000303|PubMed:15706485, ECO:0000312|HGNC:HGNC:3373}
Gene ID: 2033
Primary Accession: Q09472
NCBI Accession: NP_001420.2
Other Accession: NP_001420.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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