Phospho-ERK 1/2 (Y205/222) (7A6) Mouse mAb

Background:
Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

Cellular localization: Nucleus

Specificity: Human

Alternative Names:
MAPK, Mitogen-activated protein Kinase, PRKM2,MK01

Immunogen: Synthetic Peptide

Isotype: Mouse Monoclonal IgG1

Concentration: 1mg/ml

Recommended dilutions: IHC 1:100-200

Observed band: 44,42kDa

GeneID: 5594/5595

Swiss-Prot No.: P27361/P28482

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only