Phospho-GCN2 (Thr667) rabbit polyclonal, anti-human

Backgroud: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

Synonyms: GCN2-like protein, GCN2, KIAA1338, EIF2AK4

Gene Name: EIF2AK4

Gene ID: 440275

SwissProt ID: Q9P2K8

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.