Phospho-GRIN1(S896) Polyclonal Antibody

Background:
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Research Area: Cancer, Neuroscience

Synonyms:
GRIN1, GluN1, MRD8, NMD-R1, NMDA1, NMDAR1, NR1, NMDA 1

Immunogen: A phospho specific peptide corresponding to residues surrounding S896 of human GRIN1

Swissprot: Q05586
Gene ID: 2902

Calculated MW: 99 kDa/101 kDa/103 kDa/105 kDa/106 kDa/107 kDa
Observed MW: 120 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.