Phospho-GSK3 (Tyr279/Tyr216) rabbit polyclonal, anti-human, mouse, rat

Backgroud: GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

Synonyms: Serine/threonine-protein kinase GSK3A

Gene Name: GSK3A

Gene ID: 2931

SwissProt ID: P49840

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.