Phospho-GSK3B（Y216）/GSK3A（Y279）Polyclonal Antibody

Background:
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Stem Cells

Synonyms:
GSK3B, gsk-3β

Immunogen: A synthetic phosphorylated peptide around Y216 of human GSK3B (NP_001139628).

Swissprot: P49841
Gene ID: 2932

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100 IF 1:100-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.