Phospho-IKKα/β(S176/180) Polyclonal Antibody

Background:
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Synonyms:
CHUK, IKBKA, IKBKB, IKK-alpha, IKK-beta, IKK1, IKKA, IKKB, NFKBIKA, NFKBIKB, TCF16, IKK alpha, IKK beta

Immunogen: A synthetic phosphorylated peptide around S176 of human IKK-alpha (NP_001269.3).

Swissprot: O15111,O14920
Gene ID: 1147/3551

Calculated MW: 84 kDa/29 kDa/79 kDa/85 kDa/86 kDa
Observed MW: 85 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.