Phospho-IRS1 (Ser639) rabbit polyclonal, anti-human, mouse, rat

Backgroud: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .

Synonyms: IRS1, Insulin receptor substrate 1, IRS-1

Gene Name: IRS1

Gene ID: 3667

SwissProt ID: P35568

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.