Phospho-IRS1(Y896) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP3555a
Background:
IRS1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor it binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. It activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
Other Names:
Insulin receptor substrate 1, IRS-1, IRS1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3555a was selected from the region of human Phospho-IRS1-pY896. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: IRS1
Gene ID: 3667
Primary Accession: P35568
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
IRS1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor it binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. It activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
Other Names:
Insulin receptor substrate 1, IRS-1, IRS1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3555a was selected from the region of human Phospho-IRS1-pY896. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: IRS1
Gene ID: 3667
Primary Accession: P35568
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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