Phospho-JAK2(Y221) Polyclonal Antibody

Background:
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
JAK2, JTK10, THCYT3

Immunogen: A phospho specific peptide corresponding to residues surrounding Y221 of human JAK2

Swissprot: O60674
Gene ID: 3717

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.