Phospho-JNK/SAPK polyclonal, anti-human, mouse, rat antibody
€355.00
In stock
SKU
AC-ABV10435-100
Catalog Number: AC-ABV10435-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-α and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71.
Other Names:
c-Jun kinase, JNK , JNK 1 , JAK1A , MAPK8 , MAPK 8 , SAPK 1 , SAPK1 , Kinase JNK1 , Stress activated protein kinase
Primary Accession: P45984
Other Accession: NP_001128516
Gene Name: MAPK9
Gene ID: 5601
Concentration (mg/ml): 0.5 mg/ml
The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-α and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71.
Other Names:
c-Jun kinase, JNK , JNK 1 , JAK1A , MAPK8 , MAPK 8 , SAPK 1 , SAPK1 , Kinase JNK1 , Stress activated protein kinase
Primary Accession: P45984
Other Accession: NP_001128516
Gene Name: MAPK9
Gene ID: 5601
Concentration (mg/ml): 0.5 mg/ml
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