Phospho-KDR(Y1175) polyclonal, anti-human

Phospho-KDR(Y1175) polyclonal, anti-human

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In stock
SKU
AC-AP3710a
Catalog Number: AC-AP3710a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB25841
Applications: DB
Datasheet

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Background:
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc..

Other Names:
Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD309, KDR, FLK1, VEGFR2

Target/Specificity:
This KDR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1175 of human KDR.

Antigen Type: Synthetic Peptide

Gene Name: KDR (HGNC:6307)
Gene ID: 3791
Primary Accession: P35968
NCBI Accession: NP_002244.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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