Phospho-LIMK1(Thr508)) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP3745a
Background:
There are approximately 40 known eukaryotic LIM proteins,so named for the LIM domains they contain. LIM domains are highlyconserved cysteine-rich structures containing 2 zinc fingers.Although zinc fingers usually function by binding to DNA or RNA,the LIM motif probably mediates protein-protein interactions. LIMkinase-1 and LIM kinase-2 belong to a small subfamily with a uniquecombination of 2 N-terminal LIM motifs and a C-terminal proteinkinase domain. LIMK1 is likely to be a component of anintracellular signaling pathway and may be involved in braindevelopment. LIMK1 hemizygosity is implicated in the impairedvisuospatial constructive cognition of Williams syndrome. [providedby RefSeq].
Other Names:
LIM domain kinase 1, LIMK-1, LIMK1, LIMK
Gene Name: LIMK1
Gene ID: 3984
Primary Accession: P53667
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
There are approximately 40 known eukaryotic LIM proteins,so named for the LIM domains they contain. LIM domains are highlyconserved cysteine-rich structures containing 2 zinc fingers.Although zinc fingers usually function by binding to DNA or RNA,the LIM motif probably mediates protein-protein interactions. LIMkinase-1 and LIM kinase-2 belong to a small subfamily with a uniquecombination of 2 N-terminal LIM motifs and a C-terminal proteinkinase domain. LIMK1 is likely to be a component of anintracellular signaling pathway and may be involved in braindevelopment. LIMK1 hemizygosity is implicated in the impairedvisuospatial constructive cognition of Williams syndrome. [providedby RefSeq].
Other Names:
LIM domain kinase 1, LIMK-1, LIMK1, LIMK
Gene Name: LIMK1
Gene ID: 3984
Primary Accession: P53667
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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