Phospho-LINGO-1(LRRN6A)(S596) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP3685a
Background:
LINGO-1 (LRR and Ig domain-containing Nogo Receptor interating protein) is a nervous system-specific LRR-Ig-containing protein with an important role in CNS biology. LINGO-1 was discovered in a sequence database search for human SLIT homologs that were selectively expressed in the brain. LINGO-1 is a transmembrane protein that is a component of the Nogo-66 receptor complex. It binds NgR1 and p75 and is an additional functional componenet of the NgR1/p75 signaling complex.
Other Names:
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, Lingo1, Lern1, Lrrn6a
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3685a was selected from the LRRN6A-pS596 region of human Phospho-LINGO-1(LRRN6A)-pS596. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: Lingo1
Gene ID: 235402
Primary Accession: Q9D1T0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
LINGO-1 (LRR and Ig domain-containing Nogo Receptor interating protein) is a nervous system-specific LRR-Ig-containing protein with an important role in CNS biology. LINGO-1 was discovered in a sequence database search for human SLIT homologs that were selectively expressed in the brain. LINGO-1 is a transmembrane protein that is a component of the Nogo-66 receptor complex. It binds NgR1 and p75 and is an additional functional componenet of the NgR1/p75 signaling complex.
Other Names:
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, Lingo1, Lern1, Lrrn6a
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3685a was selected from the LRRN6A-pS596 region of human Phospho-LINGO-1(LRRN6A)-pS596. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: Lingo1
Gene ID: 235402
Primary Accession: Q9D1T0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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