Phospho-MAPKAPK2(T334) Polyclonal Antibody

Background:
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
MAPKAPK2, MAPKAP-K2, MK-2, MK2

Immunogen: A phospho specific peptide corresponding to residues surrounding T334 of human MAPKAPK2

Swissprot: P49137
Gene ID: 9261

Calculated MW: 42 kDa/45 kDa
Observed MW: 55 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.