Phospho-MEF2C(S396) Polyclonal Antibody

Background:
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction, Stem Cells

Synonyms:
MEF2C, C5DELq14.3, DEL5q14.3

Immunogen: A synthetic phosphorylated peptide around S396 of human MEF2C (NP_002388.2).

Swissprot: Q06413
Gene ID: 4208

Calculated MW: 44 kDa/47 kDa/50 kDa/51 kDa/52 kDa
Observed MW: 60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.