Phospho-mouse FADD(S191) polyclonal, anti-mouse
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In stock
SKU
AC-AP3103a
Catalog Number: AC-AP3103a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB6864
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB6864
Applications: WB
Datasheet
Request Information
Background:
FADD is an apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Other Names:
FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1
Target/Specificity:
This mouse FADD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S191 of mouse FADD.
Antigen Type: Synthetic Peptide
Gene Name: Fadd {ECO:0000303|PubMed:8649383, ECO:0000312|MGI:MGI:109324}
Gene ID: 14082
Primary Accession: Q61160
NCBI Accession: NP_034305.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
FADD is an apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Other Names:
FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1
Target/Specificity:
This mouse FADD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S191 of mouse FADD.
Antigen Type: Synthetic Peptide
Gene Name: Fadd {ECO:0000303|PubMed:8649383, ECO:0000312|MGI:MGI:109324}
Gene ID: 14082
Primary Accession: Q61160
NCBI Accession: NP_034305.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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