Phospho-mouse p27Kip1(T197) Blocking Peptide
€363.00
In stock
SKU
AC-BP3878a
Background:
This gene encodes a cyclin-dependent kinase inhibitor,which shares a limited similarity with CDK inhibitor CDKN1A/p21.The encoded protein binds to and prevents the activation of cyclinE-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycleprogression at G1. The degradation of this protein, which istriggered by its CDK dependent phosphorylation and subsequentubiquitination by SCF complexes, is required for the cellulartransition from quiescence to the proliferative state. [provided byRefSeq].
Other Names:
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, Cdkn1b
Target/Specificity:
The synthetic peptide sequence is selected from aa 190-197 of MOUSE Cdkn1b
Gene Name: Cdkn1b
Gene ID: 12576
Primary Accession: P46414
Other Accession: NP_034005.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a cyclin-dependent kinase inhibitor,which shares a limited similarity with CDK inhibitor CDKN1A/p21.The encoded protein binds to and prevents the activation of cyclinE-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycleprogression at G1. The degradation of this protein, which istriggered by its CDK dependent phosphorylation and subsequentubiquitination by SCF complexes, is required for the cellulartransition from quiescence to the proliferative state. [provided byRefSeq].
Other Names:
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, Cdkn1b
Target/Specificity:
The synthetic peptide sequence is selected from aa 190-197 of MOUSE Cdkn1b
Gene Name: Cdkn1b
Gene ID: 12576
Primary Accession: P46414
Other Accession: NP_034005.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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