Phospho-mouse TSC1(S312) polyclonal, anti-mouse
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In stock
SKU
AC-AP3812a
Catalog Number: AC-AP3812a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41229
Applications: DB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41229
Applications: DB
Datasheet
Request Information
Background:
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Other Names:
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Target/Specificity:
This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of mouse TSC1.
Antigen Type: Synthetic Peptide
Gene Name: Tsc1 {ECO:0000303|PubMed:11130985, ECO:0000312|MGI:MGI:1929183}
Gene ID: 64930
Primary Accession: Q9EP53
NCBI Accession: NP_075025.2
Other Accession: NP_075025.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Other Names:
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Target/Specificity:
This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of mouse TSC1.
Antigen Type: Synthetic Peptide
Gene Name: Tsc1 {ECO:0000303|PubMed:11130985, ECO:0000312|MGI:MGI:1929183}
Gene ID: 64930
Primary Accession: Q9EP53
NCBI Accession: NP_075025.2
Other Accession: NP_075025.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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