Phospho-MYC(T58) polyclonal, anti-human

Phospho-MYC(T58) polyclonal, anti-human

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In stock
SKU
AC-AP3325a
Catalog Number: AC-AP3325a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB11187
Applications: WB, DB
Datasheet

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Background:
MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.

Other Names:
Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39

Target/Specificity:
This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.

Antigen Type: Synthetic Peptide

Gene Name: MYC
Gene ID: 4609
Primary Accession: P01106
NCBI Accession: NP_002458.2
Other Accession: P09416; Q29031; P01108; P01109; Q2HJ27; P24793; Q63379; P03966; P04198; Q9PSJ0; P18444; P15171; Q7ZVS9; P52160; P06171; Q28566
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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