Phospho-p70 S6 Kinase polyclonal, anti-human, mouse, rat antibody
€410.00
In stock
SKU
AC-ABV10374-100
Catalog Number: AC-ABV10374-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. P70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5’oligopyrimidine tract mRNAs. A second isoform, p85 S6 kinase, is derived from the same gene and is identical to p70 S6 kinase except for 23 extra residues at the N-terminus that encode a nuclear localizing signal. Both isoforms lie on a mitogen-activated signaling pathway downstream of phosphoinositide 3 kinase (PI3K) and the target of rapamycin FRAP/mTOR, and distinct from the Ras/MAP kinase cascade.
Other Names:
RPS6KB1 , p70S6k , p70 , S6K , p70(S6K)-alpha , P70S6K , p70(S6K)-alpha , p70-alpha, Ribosomal protein S6 kinase beta-2, S6K-beta-2, S6K2, 70 kDa ribosomal protein S6 kinase 2, p70-S6K 2, P70S6K2, p70 ribosomal S6 kinase beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, S6K-beta, p70-beta, S6 kinase-related kinase, SRK, Serine/threonine-protein kinase 14B
Primary Accession: Q9UBS0
Gene Name: RPS6KB2
Gene ID: 6199
Concentration (mg/ml): 0.5 mg/ml
p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. P70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5’oligopyrimidine tract mRNAs. A second isoform, p85 S6 kinase, is derived from the same gene and is identical to p70 S6 kinase except for 23 extra residues at the N-terminus that encode a nuclear localizing signal. Both isoforms lie on a mitogen-activated signaling pathway downstream of phosphoinositide 3 kinase (PI3K) and the target of rapamycin FRAP/mTOR, and distinct from the Ras/MAP kinase cascade.
Other Names:
RPS6KB1 , p70S6k , p70 , S6K , p70(S6K)-alpha , P70S6K , p70(S6K)-alpha , p70-alpha, Ribosomal protein S6 kinase beta-2, S6K-beta-2, S6K2, 70 kDa ribosomal protein S6 kinase 2, p70-S6K 2, P70S6K2, p70 ribosomal S6 kinase beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, S6K-beta, p70-beta, S6 kinase-related kinase, SRK, Serine/threonine-protein kinase 14B
Primary Accession: Q9UBS0
Gene Name: RPS6KB2
Gene ID: 6199
Concentration (mg/ml): 0.5 mg/ml
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