Phospho-P70 S6K(T389) Polyclonal Antibody

Background:
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha, P70 S6K, RPS6KB1, p70S6KA

Immunogen: A phospho specific peptide corresponding to residues surrounding T389 of human P70 S6K

Swissprot: P23443
Gene ID: 6198

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "
IHC 1:50-1:200
IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.