Phospho-P90RSK(T359/S363) Polyclonal Antibody

Background:
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
HU-1, MAPKAPK1A, RSK, RSK1, p90Rsk, RPS6KA1

Immunogen: A synthetic phosphorylated peptide around T359 & S363 of human P90RSK (NP_002944.2).

Swissprot: Q15418
Gene ID: 6195

Calculated MW: 72 kDa/81 kDa/82 kDa/83 kDa
Observed MW: 83 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.