Phospho-PKC delta (Thr507) Polyclonal Antibody

Background:
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
CVID9, D14Ertd420e, Kinase PKC delta, KPCD, KPCD, MAY 1, MAY1, MGC49908, nPKC delta, nPKC-delta, PCKd, PKC d, PKC delta, PKCD, PKCdelta, PRKC D, PRKC delta, Prkcd, Protein Kinase C delta, Protein kinase C delta type, Protein kinase C delta VIII, Protein Kinase Cdelta, Tyrosine protein kinase PRKCD

Immunogen: Synthesized peptide derived from human PKC δ around the phosphorylation site of Thr507

Swissprot: Q05655

Calculated MW: 77 kDa
Observed MW: 78 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.