Phospho-PLB(S16) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP3692a
Background:
Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.
Other Names:
Cardiac phospholamban, PLB, PLN, PLB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3692a was selected from the region of human Phospho-PLB-pS16. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PLN (HGNC:9080)
Gene ID: 5350
Primary Accession: P26678
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.
Other Names:
Cardiac phospholamban, PLB, PLN, PLB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3692a was selected from the region of human Phospho-PLB-pS16. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PLN (HGNC:9080)
Gene ID: 5350
Primary Accession: P26678
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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