Phospho-PXN(Y118) Polyclonal Antibody

Background:
This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).

Research Area: Cancer, Signal Transduction

Synonyms:
Paxillin, PXN, paxillin

Immunogen: A phospho specific peptide corresponding to residues surrounding Y118 of human PXN

Swissprot: P49023
Gene ID: 5829

Calculated MW: 46 kDa/60 kDa/64 kDa/66 kDa
Observed MW: 70 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.